Robert Chapman

Robert Chapman
BE (Hon 1, UNSW), Ph.D (Sydney), MRSC, MRACI CChem
Lecturer and DECRA Fellow
Contact details
Phone: (02) 9385 5958
Email: r.chapman@unsw.edu.au
Office
Science and Engineering Building (SEB, E8) Room 702
Biographical Details
I completed a BEng in Industrial Chemistry (2002-07) at UNSW with a co-operative scholarship. After a year working in management consulting for the Boston Consulting Group, I moved to the University of Sydney for my PhD in Chemistry (2009-12) under Profs. Sebatien Perrier and Katrina Jolliffe, where I studied the synthesis and self assembly of cyclic peptide - polymer conjugates. I subsequently worked as a research associate in the lab of Prof. Molly Stevens at Imperial College London (2013-15) on the development of nanomaterial based biosensors and scaffolds for tissue engineering, before returning to the School of Chemistry at UNSW as a Vice-Chancellors Research Fellow in 2016. I work within the Centre for Advanced Macromolecular Design (CAMD).
Research projects
Research group
Our group works within the Centre for Advanced Macromolecular Discover (CAMD) and the Australian Centre for Nanotechnology (ACN). Please contact me by email if you are interested in joining us. Further information on the application process and available scholarships can be found at the Graduate Research School website, and at the UNSW research scholarships website.
Group photos (2019)
Current students
Zihao (Alvin) Li (PhD) | Shegufta Farazi (Honours) | Henry Foster (Honours) | ||
With Martina Stenzel: |
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Yiping Wang (PhD) | Ahmed Mustafa (PhD) | Daniele Melodia (PhD) |
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Selected publications
Please refer to my researchgate or google scholar profile for an up to date list of publications. Selected papers are listed below to give a flavour of the research I am involved in.
Farazi S, Chen F, Foster H, Boquiren R, McAlpine S, Chapman R*; Real time monitoring of peptide delivery in vitro using high payload pH responsive nanogels, Polymer Chemistry, 2020,11, 425-432 [emerging investigators issue]
Li Z, Kosuri S, Foster H, Cohen J, Jumeaux C, Stevens MM, Chapman R,* Gormley AJ*; A Dual Wavelength Polymerization and Bioconjugation Strategy for High Throughput Synthesis of Multivalent Ligands; J. Am. Chem. Soc., 2019, 141, 50, 19823-19830
Li Z, Ganda S, Melodia D, Boyer C, Chapman R*; Well-defined polymers for non-chemistry laboratories using oxygen tolerant controlled radical polymerization, J. Chemical Education, 2020, ASAP.
Tamasi M, Kosuri S, DiStefano J, Chapman R, Gormley AJ; Automation of Controlled/Living Radical Polymerization; Adv. Intelligent Systems, 2019, ASAP
Rahimi M, Foster H, Farazi S, Chapman R*, McAlpine S*; Polymer mediated transport of the Hsp90 inhibitor LB76, a polar cyclic peptide, produces an Hsp90 cellular phenotype, Chemical Communications, 2019, 55, 4515-4518.
Chapman R*, Stenzel MH; All wrapped up: Stabilization of enzymes within single enzyme nanoparticles, J. Am. Chem. Soc., 2019, 141, 7, 2754-2769
Oliver S, Zhao L, Gormley AJ, Chapman R, Boyer C; Living in the Fast Lane—High Throughput Controlled/Living Radical Polymerization, Macromolecules, 2019, 52(1), 3-23.
Yeow J, Gormley AJ, Chapman R, Boyer C; Up in the Air: Oxygen Tolerance in Controlled/Living Radical Polymerization, Chemical Society Reviews, 2018, 47, 4357-4387
Gormley AJ, Yeow J, Ng G, Conway O, Boyer C, Chapman R*; An oxygen tolerant PET-RAFT polymerisation for screening structure-activity relationships, Angewandte Chemie Int. Ed., 2018, 57 (6), 1557-1562
Yeow J, Joshi S, Chapman R, Boyer C; A Self-Reporting Photocatalyst for Online Fluorescence Monitoring of High Throughput RAFT Polymerization, Angewandte Chemie Int. Ed., 2018, 47, 4235-4666
Chen F, Raveendran R, Cao C, Chapman R, Stenzel MH, Correlation between polymer architecture and polyion complex micelle stability with proteins in spheroid cancer models as seen by light-sheet microscopy, Polymer Chemistry, 2019, 10 (10), 1221-1230
Ng G, Yeow J, Chapman R, Isahak N, Wolvetang E, Cooper-White JJ, Boyer C; Pushing the Limits of High Throughput PET-RAFT Polymerization, Macromolecules, 2018, 51 (19), 7600-7607
Ishizuka F, Chapman R, Kuchel RP, Coureault M, Zetterlund PB, Stenzel MH; Polymeric Nanocapsules for Enzyme Stabilization in Organic Solvents, Macromolecules, 2018, 51 (2), 438–446
Milner P, Parkes M, Putzer JL, Chapman R, Stevens MM, Cann P, Jeffers J; A Low Friction, Biphasic and Boundary Lubricating Hydrogel for Cartilage Replacement, Acta Biomaterialia, 2018, 65, 102-111
Chapman R*, Melodia D, Qu JB, Stenzel MH, Controlled poly(olefin)s via decarboxylation of poly(acrylic acid), Polymer Chemistry, 2017, 8, 6636-6643
Qu JB, Chapman R, Chen F, Lu H, Stenzel MH; Swollen Micelles for the Preparation of Gated, Squeezable, pH-Responsive Drug Carriers, ACS Adv. Mater. Int. , 2017, 9, 13865-13874, https://pubs.acs.org/doi/abs/10.1021/acsami.7b01120
Yeow J, Chapman R, Xu J, Boyer C; Oxygen tolerant photopolymerization for ultralow volumes, Polymer Chemistry, 2017, 8, 5012-5022
Chapman R; Gormley AJ; Stenzel MH; Stevens MM; Combinatorial Low-Volume Synthesis of Well-Defined Polymers by Enzyme Degassing, Angewandte Chemie Int. Ed., 2016, 55, 4500 - 4503
Liu NJ, Chapman R, Lin Y, Mmesi J, Bentham A, Tyreman M, Abraham S, Stevens MM; Point of care testing of phospholipase A2 group IIA for serological diagnosis of rheumatoid arthritis, Nanoscale, 2016, 8, 4482
Liu NJ; Chapman R; Lin Y; Bentham A; Tyreman M; Philips N; Khan SA; Stevens MM; Phospholipase A2 as a point of care alternative to serum amylase and pancreatic lipase, Nanoscale, 2016, 8, 11834 - 11839
Harrison RH, Steele JAM, Chapman R, Gormley AJ, Chow LW, Mahat M, Podhorska L, Hettiaratchy SP, Dunlop IE, Stevens MM; Dual functional scaffold with opposing cell adhesive and anti-adhesive surfaces generated by flexible usage of surface initiated polymer growth and peptide functionalization. Adv. Functional Mater. 2015, 25, 5748. [Cover article]
Jumeaux C, Chapman R, Chandrawati R, Stevens MM; Synthesis and self-assembly of temperature-responsive copolymers based on N-vinylpyrrolidone and triethylene glycol methacrylate. Polymer Chemistry, 2015, 6, 4116
Lin Y, Chapman R, Stevens MM; Integrative self-assembly of graphene quantum dot and biopolymer into a versatile biosensing toolkit. Adv. Functional Mater. 2015, 25, 3183.
Chapman R; Lin Y; Burnapp M; Bentham A; Hillier D; Zabron A; Khan S; Tyreman M; Stevens MM; Multivalent Nanoparticle Networks Enable Point-of-Care Detection of Human Phospholipase-A2 in Serum, ACS Nano, 2015, 9, 2565 - 2573
Chapman R, Gormley AJ, Herpoldt KL, Stevens MM; Highly controlled open vessel RAFT polymerizations by enzyme degassing, Macromolecules, 2014, 47, 8541
Gormley AJ; Chapman R; Stevens MM; Polymerization Amplified Detection for Nanoparticle-Based Biosensing, Nano Letters, 2014, 14, 6368-6373
Lin Y, Chapman R, Stevens MM; Label-free multimodal protease detection based on protein/perylene dye coassembly and enzyme-triggered disassembly. Analytical Chemistry, 2014, 86, 6410.
Blunden BM, Chapman R, Danial M, Lu H, Jolliffe KA, Perrier S, Stenzel MH; Drug conjugation to cyclic Peptide-polymer self-assembling nanotubes. Chemistry - A European Journal, 2014, 20, 12745.
Chapman R, Bouten P, Hoogenboom R, Jolliffe KA, Perrier S; Thermoresponsive cyclic peptide – poly(2-ethyl-2-oxazoline) conjugate nanotubes. Chemical Communications, 2013, 49, 6522.
Chapman R; Koh ML; Warr GG; Jolliffe KA; Perrier S; Structure elucidation and control of cyclic peptide-derived nanotube assemblies in solution, Chemical Science, 2013, 4, 2581 - 2581
Chapman R; Jolliffe KA; Perrier S; Multi-shell Soft Nanotubes from Cyclic Peptide Templates, Advanced Materials, 2013, 25, 1170 - 1172
Chapman R, Warr GG, Jolliffe KA, Perrier S; Water-Soluble and pH-Responsive Polymeric Nanotubes from Cyclic Peptide Templates. Chemistry - A European Journal, 2013, 19, 1955.
Chapman R; Danial M; Koh ML; Jolliffe KA; Perrier S; Design and properties of functional nanotubes from the self-assembly of cyclic peptide templates, Chemical Society Reviews, 2012, 41, 6023 - 6023
Wilkinson BL, Day S, Chapman R, Perrier S, Apostolopoulos V, Payne RJ; Synthesis and Immunological Evaluation of Self-Assembling and Self-Adjuvanting Tricomponent Glycopeptide Cancer-Vaccine Candidates. Chemistry - A European Journal, 2012, 18, 16540.
Junkers T, Delaittre G, Chapman R, Günzler F, Chernikova E, Barner-Kowollik C; Thioketone-Mediated Polymerization with Dithiobenzoates: Proof for the Existence of Stable Radical Intermediates in RAFT Polymerization. Macromolecular Rapid Communications, 2012, 33, 984.
Poon CK, Chapman R, Jolliffe KA, Perrier S; Pushing the limits of copper mediated azide-alkyne cycloaddition (CuAAC) to conjugate polymeric chains to cyclic peptides. Polymer Chemistry, 2012, 3, 1820.
Chapman R; Jolliffe KA; Perrier S; Modular design for the controlled production of polymeric nanotubes from polymer/peptide conjugates, Polymer Chemistry, 2011, 2, 1956 - 1956
Dehn S, Chapman R, Jolliffe KA, Perrier S; Synthetic Strategies for the Design of Peptide / Polymer Conjugates. Polymer Reviews, 2011, 51, 214.
Chapman R, Jolliffe KA, Perrier S; Synthesis of Self-assembling Cyclic Peptide-polymer Conjugates using Click Chemistry. Australian Journal of Chemistry, 2010, 63, 1169.