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Welcome to the web page of the Biosensors and Biointerfaces research group at UNSW led by Scientia Professor Justin Gooding. We specialise in the molecule level modification of surfaces using self-assembled monolayers, biological molecules and nanomaterials to impart a desired functionality to that surface such as to:
- Selectively detect an analyte – biosensors and nanodiagnostics
- Influence biological processes – biomaterials and nanotherapeutics
- Allow efficient electrical communication with biological molecules - bioelectronics
- To enable fundamental studies into electron transfer at surfaces - molecules electronics
The research group has around 30 members working on a variety of research projects funded through the Australian Research Council Discovery, Linkage and Centre of Excellence programs as well as, the National Health and Medical Research Council and a variety of industrial sponsors.
The group is also part of the Australian Centre for NanoMedicine of which Professor Gooding is one of the three directors. As a result much of our research has a nanomedicine focus where we modify surfaces for diagnostic devices, imaging and biomaterials as well as more fundamental work on electron transfer, catalysis and cell-surface interactions.
There are eight main research projects in the group:
- Immunosensors for the detection of small molecules and protein biomarkers (with a US-based biosensing company) (details...)
- Electrochemical detection of microRNA in clinical samples (with Professor Maria Kavallaris, Medicine, UNSW).
- Modified porous silicon photonic crystals for developing cell chips for personalized medicine, toxin detection and nanotoxicology (with Dr. Peter Reece, Physics UNSW and Prof Katharina Gaus, Medicine UNSW, (details...).
- Nanoparticle-based biosensors for ultrasensitive detection for medical diagnostics (with Professor Rose Amal, Chemical Engineering, UNSW) (details...).
- Nanostructured surfaces for understanding fundamental cellular processes (in collaboration with Professor Katharina Gaus, Medicine UNSW).
- The 3D printing of cell cultures (with Professor Maria Kavallaris, Medicine UNSW).
- Electrochemistry and molecular electronics at silicons surfaces (details...).
- The immobilisation of homogeneous catalyst on surfaces (led by Professor Barbara Messerle, Chemistry UNSW)
These different projects are explained in more detail on the research pages.