B.Sc. (Hons) Melb. 1988, D. Phil. (Oxon) 1994, CChem, FRACI, FRSC
Scientia Professor and founding co-director of The Australian Centre for NanoMedicine
Phone: (02) 9385 5384
Fax: (02) 9385 6141
OfficeRoom 125 Dalton Building, F12
UNSW, Kensington 2052
Research Group Website
Graduate of Oxford University (D. Phil., 1994). Postdoctoral Fellow, University of Cambridge, (1994-1996). Vice-Chancellor's Postdoctoral Research Fellow, UNSW (1997-1998). Lecturer, Flinders University of South Australia (1998). Appointed Lecturer at UNSW (1999), Senior Lecturer (2002), Associate Professor (2006), Professor (2006), UNSW Scientia Professor (2011).
NSW Young Tall Poppy Science Prize (2004), Alexander von Humboldt Fellowship (2005), University of Canterbury Erskine Fellow (2007), Royal Australian Chemical Institute Analytical Chemistry Division Lloyd Smythe Medal (2007), Eureka Prize for Scientific Research (2009), ARC Australian Professorial Fellow (2010-2104), Royal Australian Chemical Institute H.G. Smith Medal (2011), Royal Australian Chemical Institute Electrochemistry Division R.H. Stokes Medal (2012), Royal Society of Chemistry Australasian Lecturer (2012), NSW Science and Engineering Award for Emerging Research (2013).
Chair, The Royal Australian Chemical Institute Electrochemistry Division 2006-2011, Inaugural Australian Representative of the International Society of Electrochemistry 2011-2012, Vice President International Society of Electrochemistry 2013-2015
Our research group specialises in the molecule level modification of surfaces using self-assembled monolayers, biological molecules and nanomaterials to impart a desired functionality to that surface such as to:
1. Selectively detect an analyte – biosensors and nanodiagnostics
2. Influence biological processes – biomaterials and nanotherapeutics
3. Allow efficient electrical communication with biological molecules - bioelectronics
4.To enable fundamental studies into electron transfer at surfaces - molecules electronics
The group is also part of the Australian Centre for NanoMedicine of which Professor Gooding is one of the three directors. As a result much of our research has a nanomedicine focus where we modify surfaces for diagnostic devices, imaging and biomaterials as well as more fundamental work on electron transfer, catalysis and cell-surface interactions.
1.Immunosensors for the detection of small molecules and for protein biomarkers.
2.Electrochemical detection of MicroRNA in clinical samples (with Professor Maria Kavallaris, Medicine UNSW).
3.Modified porous silicon photonic crystals for developing cell chips for personalized medicine, toxin detection and nanotoxicology (with Dr. Peter Reece, Physics UNSW and Prof Katharina Gaus, Medicine UNSW).
4.Nanoparticle based biosensors for ultrasensitive detection for medical diagnostics (with Professor Rose Amal, Chemical Engineering, UNSW).
5.Nanostructured surfaces for understanding fundamental cellular processes (in collaboration with Professor Katharina Gaus, Medicine UNSW).
6.The 3D printing of cell cultures (with Professor Maria Kavallaris, Medicine UNSW).
7.Electrochemistry and molecular electronics on silicon surfaces (with Dr Simone Ciampi, University of Wollongong).
8.The immobilisation of homogeneous catalyst on surfaces (led by Professor Barbara Messerle, Chemistry UNSW).
The research group is typically between 30 people in size with 5 post-docs, 15 or so Ph.D. students and 3-4 honours students and visitors. We create a supportive environment where all researchers work in teams on related projects with junior researchers being assisted by post-docs and senior Ph.D. students as well as Prof. Gooding. As our research involves a range of techniques all researchers acquire a broad range of skills but typically specialise in one or two techniques. Ph.D. students usually complete within 3½ years with 5-10 research publications. Using our team-oriented approach our research group has published over 100 papers within the last five years. Representative publications are listed below.
- A. Tregubov, K.Q. Vuong, E. Luais, J.J. Gooding, B.A. Messerle, Rh(I) Complexes Bearing N,N and N,P Ligands Anchored on Glassy Carbon Electrodes: towards Recyclable Hydroamination Catalysts, J. Am. Chem. Soc. 135 16429−16437 (2013)
- C.C.A. Ng, A. Magenau, S.H. Ngalim, S. Ciampi, M. Chockalingham, J.B. Harper, K. Gaus, J.J. Gooding, Using Electrical Potential to Reversibly Switch Surfaces between Two States for Dynamically Controlling Cell Adhesion, Angew. Chem. Int. Ed. 51 7706-7710 (2012).
- L.M.H. Lai, I.Y. Goon, K. Chuah, M. Lim, F. Braet, R. Amal, J.J. Gooding, Biochemiresistor Sensor– A New Type of Biosensor Employing Magnetic Assembly of Gold Coated Magnetic Nanoparticles, Angew. Chem. Int. Ed. 51 6456-6459 (2012).
- P.K. Eggers, N. Darwish, M.N. Paddon-Row, J.J. Gooding, Surface-Bound Molecular Rulers for Probing the Electrical Double Layer, J. Am. Chem. Soc. 134 7539-7544 (2012).
- S. Ciampi, M. James, G. Le Saux, K. Gaus, J.J. Gooding, Electrochemical ‘Switching’ of Silicon(100) Modular Assemblies for Cell Biology, J. Am. Chem. Soc. 134 844-847 (2012).
- N. Darwish, I. Diez-Pérez, P. Da Silva, N.J. Tao, J.J. Gooding, M.N. Paddon-Row, Observation of Electrochemically Controlled Quantum Interference in a Single Anthraquinone-based Norbornylogous Bridge Molecule, Angew. Chem. Int. Ed. 51 3203-3206 (2012).
- D.J. Williamson, D.M. Owen, J. Rossy, M. Wehrmann, A. Magenau, J.J. Gooding, K. Gaus, Pre-existing LAT clusters do not participate in early T cell signaling events, Nature Immunology 12 655-662 (2011).
- D. Li, W.Y. Teoh, J.J. Gooding, C. Selomulya, R. Amal, Functionalisation Strategies for Protease Immobilisation on Magnetic Nanoparticles, Adv. Funct. Mater. 20 1767-1777 (2010).
- K.A. Kilian, L.M.H. Lai, A. Magenau, S. Cartland, T. Böcking, N. Di Girolamo, M. Gal, K. Gaus, J.J. Gooding, Smart Tissue Culture: In Situ Monitoring of Cellular Secretion With Nanostructured Photonic Crystals NanoLett. 9 2021-2025 (2009).
- G.Z. Liu, M.N. Paddon-Row, J.J. Gooding, Protein Modulation of Electrochemical Signals: Application to Immunobiosensing for Detecting Small Molecules, Chem. Comm. 3870-3872 (2008).